Cargando…
A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients
The aims of the present study were to develop and check the utility and feasibility of a novel right ventricular (RV) functional index (RV angular velocity; RVω, s(−1)) derived from the angular velocity in harmonic oscillator kinematics obtained from the RV pressure waveform. We hypothesized that RV...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934714/ https://www.ncbi.nlm.nih.gov/pubmed/31882794 http://dx.doi.org/10.1038/s41598-019-56564-y |
_version_ | 1783483447547789312 |
---|---|
author | Hayabuchi, Yasunobu Homma, Yukako Kagami, Shoji |
author_facet | Hayabuchi, Yasunobu Homma, Yukako Kagami, Shoji |
author_sort | Hayabuchi, Yasunobu |
collection | PubMed |
description | The aims of the present study were to develop and check the utility and feasibility of a novel right ventricular (RV) functional index (RV angular velocity; RVω, s(−1)) derived from the angular velocity in harmonic oscillator kinematics obtained from the RV pressure waveform. We hypothesized that RVω reflects the myocardial performance index (MPI), which represents global RV function. A total of 132 consecutive patients, ranging in age from 3 months to 34 years with various cardiac diseases were included in this prospective study. RVω was defined as the difference between the peak derivative of pressure (dP/dt_max − dP/dt_min) divided by the difference between the maximum and minimum pressure (Pmax – Pmin). RVω showed significant negative correlations with the pulsed-wave Doppler-derived myocardial performance index (PWD-MPI) and the tissue Doppler imaging-derived MPI (TDI-MPI) (r = −0.52 and −0.51, respectively; both p < 0.0001). RVω also showed significant positive correlations with RV fractional area change (RVFAC) and RV ejection fraction (RVEF) (r = 0.41 and 0.39, respectively; both p < 0.0001), as well as a significant negative correlation with tricuspid E/e′ (r = −0.19, p = 0.0283). The clinical feasibility and utility of RVω for assessing global RV performance, incorporating both systolic and diastolic function, were demonstrated. |
format | Online Article Text |
id | pubmed-6934714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-69347142019-12-30 A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients Hayabuchi, Yasunobu Homma, Yukako Kagami, Shoji Sci Rep Article The aims of the present study were to develop and check the utility and feasibility of a novel right ventricular (RV) functional index (RV angular velocity; RVω, s(−1)) derived from the angular velocity in harmonic oscillator kinematics obtained from the RV pressure waveform. We hypothesized that RVω reflects the myocardial performance index (MPI), which represents global RV function. A total of 132 consecutive patients, ranging in age from 3 months to 34 years with various cardiac diseases were included in this prospective study. RVω was defined as the difference between the peak derivative of pressure (dP/dt_max − dP/dt_min) divided by the difference between the maximum and minimum pressure (Pmax – Pmin). RVω showed significant negative correlations with the pulsed-wave Doppler-derived myocardial performance index (PWD-MPI) and the tissue Doppler imaging-derived MPI (TDI-MPI) (r = −0.52 and −0.51, respectively; both p < 0.0001). RVω also showed significant positive correlations with RV fractional area change (RVFAC) and RV ejection fraction (RVEF) (r = 0.41 and 0.39, respectively; both p < 0.0001), as well as a significant negative correlation with tricuspid E/e′ (r = −0.19, p = 0.0283). The clinical feasibility and utility of RVω for assessing global RV performance, incorporating both systolic and diastolic function, were demonstrated. Nature Publishing Group UK 2019-12-27 /pmc/articles/PMC6934714/ /pubmed/31882794 http://dx.doi.org/10.1038/s41598-019-56564-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Hayabuchi, Yasunobu Homma, Yukako Kagami, Shoji A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
title | A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
title_full | A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
title_fullStr | A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
title_full_unstemmed | A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
title_short | A novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
title_sort | novel index equivalent to the myocardial performance index for right ventricular functional assessment in children and adolescent patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934714/ https://www.ncbi.nlm.nih.gov/pubmed/31882794 http://dx.doi.org/10.1038/s41598-019-56564-y |
work_keys_str_mv | AT hayabuchiyasunobu anovelindexequivalenttothemyocardialperformanceindexforrightventricularfunctionalassessmentinchildrenandadolescentpatients AT hommayukako anovelindexequivalenttothemyocardialperformanceindexforrightventricularfunctionalassessmentinchildrenandadolescentpatients AT kagamishoji anovelindexequivalenttothemyocardialperformanceindexforrightventricularfunctionalassessmentinchildrenandadolescentpatients AT hayabuchiyasunobu novelindexequivalenttothemyocardialperformanceindexforrightventricularfunctionalassessmentinchildrenandadolescentpatients AT hommayukako novelindexequivalenttothemyocardialperformanceindexforrightventricularfunctionalassessmentinchildrenandadolescentpatients AT kagamishoji novelindexequivalenttothemyocardialperformanceindexforrightventricularfunctionalassessmentinchildrenandadolescentpatients |