Proteomic and Transcriptomic Changes in Hibernating Grizzly Bears Reveal Metabolic and Signaling Pathways that Protect against Muscle Atrophy

Muscle atrophy is a physiological response to disuse and malnutrition, but hibernating bears are largely resistant to this phenomenon. Unlike other mammals, they efficiently reabsorb amino acids from urine, periodically activate muscle contraction, and their adipocytes differentially responds to ins...

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Detalles Bibliográficos
Autores principales: Mugahid, D. A., Sengul, T. G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M. H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C. T., Völker, U., Chen, W., Nelson, L., Gotthardt, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934745/
https://www.ncbi.nlm.nih.gov/pubmed/31882638
http://dx.doi.org/10.1038/s41598-019-56007-8

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