Cargando…

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Metabolic diseases such as obesity, type II diabetes and hepatic steatosis are a public health concern in developed countries. The metabolic risk is gender‐dependent. The constitutive androstane receptor (CAR), which is at the crossroads between energy metabolism and endocrinology, has recently emer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lukowicz, Céline, Ellero-Simatos, Sandrine, Régnier, Marion, Oliviero, Fabiana, Lasserre, Frédéric, Polizzi, Arnaud, Montagner, Alexandra, Smati, Sarra, Boudou, Frédéric, Lenfant, Françoise, Guzylack-Pirou, Laurence, Menard, Sandrine, Barretto, Sharon, Fougerat, Anne, Lippi, Yannick, Naylies, Claire, Bertrand-Michel, Justine, Belgnaoui, Afifa Ait, Theodorou, Vassilia, Marchi, Nicola, Gourdy, Pierre, Gamet-Payrastre, Laurence, Loiseau, Nicolas, Guillou, Hervé, Mselli-Lakhal, Laïla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934754/ https://www.ncbi.nlm.nih.gov/pubmed/31882815 http://dx.doi.org/10.1038/s41598-019-56570-0

Ejemplares similares

Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
por: Lukowicz, Céline, et al.
Publicado: (2020)

The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice
por: Barretto, Sharon Ann, et al.
Publicado: (2021)

Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor
por: Lukowicz, Céline, et al.
Publicado: (2018)

Gene Expression Profiling Reveals that PXR Activation Inhibits Hepatic PPARα Activity and Decreases FGF21 Secretion in Male C57Bl6/J Mice
por: Barretto, Sharon Ann, et al.
Publicado: (2019)

Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants
por: Rives, Clémence, et al.
Publicado: (2020)

Constitutive Androstane Receptor: A Peripheral and a Neurovascular Stress or Environmental Sensor
por: Oliviero, Fabiana, et al.
Publicado: (2020)

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity
por: Régnier, Marion, et al.
Publicado: (2020)

Pre- and Postnatal Dietary Exposure to a Pesticide Cocktail Disrupts Ovarian Functions in 8-Week-Old Female Mice
por: Dopavogui, Léonie, et al.
Publicado: (2022)

Dual extraction of mRNA and lipids from a single biological sample
por: Podechard, Normand, et al.
Publicado: (2018)

Sex differences in metabolic regulation and diabetes susceptibility
por: Tramunt, Blandine, et al.
Publicado: (2019)

Gut dysbiosis and impairment of immune system homeostasis in perinatally-exposed mice to Bisphenol A precede obese phenotype development
por: Malaisé, Yann, et al.
Publicado: (2017)

Hepatic Fasting-Induced PPARα Activity Does Not Depend on Essential Fatty Acids
por: Polizzi, Arnaud, et al.
Publicado: (2016)

The gut microbiota: a major player in the toxicity of environmental pollutants?
por: Claus, Sandrine P, et al.
Publicado: (2017)

The gut microbiota: a major player in the toxicity of environmental pollutants?
por: Claus, Sandrine P, et al.
Publicado: (2016)

Early Life Exposure to Food Contaminants and Social Stress as Risk Factor for Metabolic Disorders Occurrence?—An Overview
por: Guzylack-Piriou, Laurence, et al.
Publicado: (2021)

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
por: Montagner, Alexandra, et al.
Publicado: (2016)

CAR Protects Females from Diet-Induced Steatosis and Associated Metabolic Disorders
por: Oliviero, Fabiana, et al.
Publicado: (2023)

Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling
por: Ducheix, Simon, et al.
Publicado: (2017)

Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions
por: Smith, Lorraine, et al.
Publicado: (2020)

Combined Transcriptomic–(1)H NMR Metabonomic Study Reveals That Monoethylhexyl Phthalate Stimulates Adipogenesis and Glyceroneogenesis in Human Adipocytes
por: Ellero-Simatos, Sandrine, et al.
Publicado: (2011)

Depletion of Gram-Positive Bacteria Impacts Hepatic Biological Functions During the Light Phase
por: Oh, Hui Yun Penny, et al.
Publicado: (2019)

Perinatal Exposure to a Low Dose of Bisphenol A Impaired Systemic Cellular Immune Response and Predisposes Young Rats to Intestinal Parasitic Infection
por: Ménard, Sandrine, et al.
Publicado: (2014)

Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation
por: Martin, Océane C. B., et al.
Publicado: (2019)

Perinatal oral exposure to low doses of bisphenol A, S or F impairs immune functions at intestinal and systemic levels in female offspring mice
por: Malaisé, Yann, et al.
Publicado: (2020)

Bisphenol A, S or F mother’s dermal impregnation impairs offspring immune responses in a dose and sex-specific manner in mice
por: Malaisé, Yann, et al.
Publicado: (2021)

Estrogen receptor subcellular localization and cardiometabolism
por: Gourdy, Pierre, et al.
Publicado: (2018)

Changes in Intestinal Glucocorticoid Sensitivity in Early Life Shape the Risk of Epithelial Barrier Defect in Maternal-Deprived Rats
por: Moussaoui, Nabila, et al.
Publicado: (2014)

The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
por: Schoeler, Marc, et al.
Publicado: (2023)

Signaling control of the constitutive androstane receptor (CAR)
por: Yang, Hui, et al.
Publicado: (2014)

Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium
por: Gagniac, Laurine, et al.
Publicado: (2020)

Redetermination of 5α-androstane-3,17-dione
por: Jasinski, Jerry P., et al.
Publicado: (2010)

Noncanonical Constitutive Androstane Receptor Signaling in Gene Regulation
por: Pustylnyak, Yuliya A., et al.
Publicado: (2020)

Microbial Modifications of Androstane and Androstene Steroids by Penicillium vinaceum
por: Panek, Anna, et al.
Publicado: (2020)

Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR
por: Küblbeck, Jenni, et al.
Publicado: (2020)

Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease
por: Fougerat, Anne, et al.
Publicado: (2020)

Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice
por: Guillaume, Maeva, et al.
Publicado: (2019)

2a,3a-Dihydroxyandrostan-16-one
por: Zhang, Li, et al.
Publicado: (2009)

β-catenin signaling, the constitutive androstane receptor and their mutual interactions
por: Braeuning, Albert, et al.
Publicado: (2020)

Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation
por: Juang, Shin-Hun, et al.
Publicado: (2020)

Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling
por: Ellero-Simatos, Sandrine, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_147pu37sql37nmtl7qeuiqs2ko