Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies

Lumpy skin disease (LSD) is a devastating disease of cattle characterized by fever, nodules on the skin, lymphadenopathy and milk drop. Several haematophagous arthropod species like dipterans and ticks are suspected to play a role in the transmission of LSDV. Few conclusive data are however availabl...

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Autores principales: Sohier, C., Haegeman, A., Mostin, L., De Leeuw, I., Campe, W. Van, De Vleeschauwer, A., Tuppurainen, E. S. M., van den Berg, T., De Regge, N., De Clercq, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934832/
https://www.ncbi.nlm.nih.gov/pubmed/31882819
http://dx.doi.org/10.1038/s41598-019-56605-6
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author Sohier, C.
Haegeman, A.
Mostin, L.
De Leeuw, I.
Campe, W. Van
De Vleeschauwer, A.
Tuppurainen, E. S. M.
van den Berg, T.
De Regge, N.
De Clercq, K.
author_facet Sohier, C.
Haegeman, A.
Mostin, L.
De Leeuw, I.
Campe, W. Van
De Vleeschauwer, A.
Tuppurainen, E. S. M.
van den Berg, T.
De Regge, N.
De Clercq, K.
author_sort Sohier, C.
collection PubMed
description Lumpy skin disease (LSD) is a devastating disease of cattle characterized by fever, nodules on the skin, lymphadenopathy and milk drop. Several haematophagous arthropod species like dipterans and ticks are suspected to play a role in the transmission of LSDV. Few conclusive data are however available on the importance of biting flies and horseflies as potential vectors in LSDV transmission. Therefore an in vivo transmission study was carried out to investigate possible LSDV transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies from experimentally infected viraemic donor bulls to acceptor bulls. LSDV transmission by Stomoxys calcitrans was evidenced in 3 independent experiments, LSDV transmission by Haematopota spp. was shown in one experiment. Evidence of LSD was supported by induction of nodules and virus detection in the blood of acceptor animals. Our results are supportive for a mechanical transmission of the virus by these vectors.
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spelling pubmed-69348322019-12-31 Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies Sohier, C. Haegeman, A. Mostin, L. De Leeuw, I. Campe, W. Van De Vleeschauwer, A. Tuppurainen, E. S. M. van den Berg, T. De Regge, N. De Clercq, K. Sci Rep Article Lumpy skin disease (LSD) is a devastating disease of cattle characterized by fever, nodules on the skin, lymphadenopathy and milk drop. Several haematophagous arthropod species like dipterans and ticks are suspected to play a role in the transmission of LSDV. Few conclusive data are however available on the importance of biting flies and horseflies as potential vectors in LSDV transmission. Therefore an in vivo transmission study was carried out to investigate possible LSDV transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies from experimentally infected viraemic donor bulls to acceptor bulls. LSDV transmission by Stomoxys calcitrans was evidenced in 3 independent experiments, LSDV transmission by Haematopota spp. was shown in one experiment. Evidence of LSD was supported by induction of nodules and virus detection in the blood of acceptor animals. Our results are supportive for a mechanical transmission of the virus by these vectors. Nature Publishing Group UK 2019-12-27 /pmc/articles/PMC6934832/ /pubmed/31882819 http://dx.doi.org/10.1038/s41598-019-56605-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sohier, C.
Haegeman, A.
Mostin, L.
De Leeuw, I.
Campe, W. Van
De Vleeschauwer, A.
Tuppurainen, E. S. M.
van den Berg, T.
De Regge, N.
De Clercq, K.
Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies
title Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies
title_full Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies
title_fullStr Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies
title_full_unstemmed Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies
title_short Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies
title_sort experimental evidence of mechanical lumpy skin disease virus transmission by stomoxys calcitrans biting flies and haematopota spp. horseflies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934832/
https://www.ncbi.nlm.nih.gov/pubmed/31882819
http://dx.doi.org/10.1038/s41598-019-56605-6
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