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Verteporfin-Loaded Anisotropic Poly(Beta-Amino Ester)-Based Micelles Demonstrate Brain Cancer-Selective Cytotoxicity and Enhanced Pharmacokinetics
BACKGROUND: Nanomedicine can improve traditional therapies by enhancing the controlled release of drugs at targeted tissues in the body. However, there still exists disease- and therapy-specific barriers that limit the efficacy of such treatments. A major challenge in developing effective therapies...
Autores principales: | Shamul, James G, Shah, Sagar R, Kim, Jayoung, Schiapparelli, Paula, Vazquez-Ramos, Carla A, Lee, Ben J, Patel, Kisha K, Shin, Alyssa, Quinones-Hinojosa, Alfredo, Green, Jordan J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935022/ https://www.ncbi.nlm.nih.gov/pubmed/31920302 http://dx.doi.org/10.2147/IJN.S231167 |
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