Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury

BACKGROUND: Recovery of function from traumatic nerve injury depends on the ability of severed axons to grow/regenerate back to their target tissues. This is achieved by successfully crossing the lesion site where physical impact severed axons, determined by the type of trauma, followed by successfu...

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Detalles Bibliográficos
Autores principales: Elberg, Gerard, Liraz-Zaltsman, Sigal, Reichert, Fanny, Matozaki, Takashi, Tal, Michael, Rotshenker, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935070/
https://www.ncbi.nlm.nih.gov/pubmed/31883525
http://dx.doi.org/10.1186/s12974-019-1679-x

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