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HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells

BACKGROUND: Hypoxia-inducible factors (HIF)1 and 2 are transcription factors that regulate the homeostatic response to low oxygen conditions. Since data related to the importance of HIF1 and 2 in hematopoietic stem and progenitors is conflicting, we investigated the chromatin binding profiles of HIF...

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Detalles Bibliográficos
Autores principales:	Wierenga, Albertus T. J., Cunningham, Alan, Erdem, Ayşegül, Lopera, Nuria Vilaplana, Brouwers-Vos, Annet Z., Pruis, Maurien, Mulder, André B., Günther, Ulrich L., Martens, Joost H. A., Vellenga, Edo, Schuringa, Jan Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935105/ https://www.ncbi.nlm.nih.gov/pubmed/31890203 http://dx.doi.org/10.1186/s40170-019-0206-y

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