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A ligation-based single-stranded library preparation method to analyze cell-free DNA and synthetic oligos

BACKGROUND: Cell-free DNA (cfDNA), present in circulating blood plasma, contains information about prenatal health, organ transplant reception, and cancer presence and progression. Originally developed for the genomic analysis of highly degraded ancient DNA, single-stranded DNA (ssDNA) library prepa...

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Detalles Bibliográficos
Autores principales:	Troll, Christopher J., Kapp, Joshua, Rao, Varsha, Harkins, Kelly M., Cole, Charles, Naughton, Colin, Morgan, Jessica M., Shapiro, Beth, Green, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935139/ https://www.ncbi.nlm.nih.gov/pubmed/31881841 http://dx.doi.org/10.1186/s12864-019-6355-0

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