Inhibitory effects of SEL201 in acute myeloid leukemia

MAPK interacting kinase (MNK), a downstream effector of mitogen-activated protein kinase (MAPK) pathways, activates eukaryotic translation initiation factor 4E (eIF4E) and plays a key role in the mRNA translation of mitogenic and antiapoptotic genes in acute myeloid leukemia (AML) cells. We examined...

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Detalles Bibliográficos
Autores principales: Kosciuczuk, Ewa M., Kar, Aroop K., Blyth, Gavin T., Fischietti, Mariafausta, Abedin, Sameem, Mina, Alain A., Siliezar, Rebekah, Rzymski, Tomasz, Brzozka, Krzysztof, Eklund, Elizabeth A., Beauchamp, Elspeth M., Eckerdt, Frank, Saleiro, Diana, Platanias, Leonidas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935253/
https://www.ncbi.nlm.nih.gov/pubmed/31903169
http://dx.doi.org/10.18632/oncotarget.27388

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