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ISG15 induction is required during L1-mediated colon cancer progression and metastasis

Hyperactivation of Wnt/β-catenin target gene expression is a hallmark of colorectal cancer (CRC) development. We identified L1-CAM (L1) and Nr-CAM, members of the immunoglobulin family of nerve cell adhesion receptors, as target genes of the Wnt/β-catenin pathway in CRC cells. L1 overexpression in C...

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Detalles Bibliográficos
Autores principales:	Cheriyamundath, Sanith, Basu, Sayon, Haase, Gal, Doernberg, Harry, Gavert, Nancy, Brabletz, Thomas, Ben-Ze’ev, Avri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935256/ https://www.ncbi.nlm.nih.gov/pubmed/31903170 http://dx.doi.org/10.18632/oncotarget.27390

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