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A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway

PURPOSE: S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H(2)S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its clinical application. To overcome these issues,...

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Detalles Bibliográficos
Autores principales: Tran, Ba Hieu, Yu, Ying, Chang, Lingling, Tan, Bo, Jia, Wanwan, Xiong, Ying, Dai, Tao, Zhong, Rui, Zhang, Weiping, Le, Van Minh, Rose, Peter, Wang, Zhijun, Mao, Yicheng, Zhu, Yi Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935304/
https://www.ncbi.nlm.nih.gov/pubmed/31920303
http://dx.doi.org/10.2147/IJN.S216667

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