The Bdnf and Npas4 genes are targets of HDAC3-mediated transcriptional repression

BACKGROUND: Histone deacetylase-3 (HDAC3) promotes neurodegeneration in various cell culture and in vivo models of neurodegeneration but the mechanism by which HDAC3 exerts neurotoxicity is not known. HDAC3 is known to be a transcriptional co-repressor. The goal of this study was to identify transcr...

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Detalles Bibliográficos
Autores principales: Louis Sam Titus, Anto Sam Crosslee, Sharma, Dharmendra, Kim, Min Soo, D’Mello, Santosh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935488/
https://www.ncbi.nlm.nih.gov/pubmed/31883511
http://dx.doi.org/10.1186/s12868-019-0546-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935488/
https://www.ncbi.nlm.nih.gov/pubmed/31883511
http://dx.doi.org/10.1186/s12868-019-0546-0

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