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Evolution and Diversity of Assembly-Line Polyketide Synthases: Focus Review

[Image: see text] Assembly-line polyketide synthases (PKSs) are among the most complex protein machineries known in nature, responsible for the biosynthesis of numerous compounds used in the clinic. Their present-day diversity is the result of an evolutionary path that has involved the emergence of...

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Detalles Bibliográficos
Autores principales: Nivina, Aleksandra, Yuet, Kai P., Hsu, Jake, Khosla, Chaitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935866/
https://www.ncbi.nlm.nih.gov/pubmed/31838842
http://dx.doi.org/10.1021/acs.chemrev.9b00525