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Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution

BACKGROUND: We sought to evaluate the epidemiology of intracranial aneurysms in relation to location, gender, age, presence of multiple aneurysms, and comorbidities in the Brazilian population. METHODS: We performed a prospective analysis of a cohort of 1404 patients diagnosed with intracranial aneu...

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Autores principales: Júnior, Jefferson Rosi, Telles, João Paulo Mota, da Silva, Saul Almeida, Iglesio, Ricardo Ferrareto, Brigido, Mauricio Mandel, Pereira Caldas, José Guilherme Mendes, Teixeira, Manoel Jacobsen, Figueiredo, Eberval Gadelha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935967/
https://www.ncbi.nlm.nih.gov/pubmed/31893150
http://dx.doi.org/10.25259/SNI_443_2019
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author Júnior, Jefferson Rosi
Telles, João Paulo Mota
da Silva, Saul Almeida
Iglesio, Ricardo Ferrareto
Brigido, Mauricio Mandel
Pereira Caldas, José Guilherme Mendes
Teixeira, Manoel Jacobsen
Figueiredo, Eberval Gadelha
author_facet Júnior, Jefferson Rosi
Telles, João Paulo Mota
da Silva, Saul Almeida
Iglesio, Ricardo Ferrareto
Brigido, Mauricio Mandel
Pereira Caldas, José Guilherme Mendes
Teixeira, Manoel Jacobsen
Figueiredo, Eberval Gadelha
author_sort Júnior, Jefferson Rosi
collection PubMed
description BACKGROUND: We sought to evaluate the epidemiology of intracranial aneurysms in relation to location, gender, age, presence of multiple aneurysms, and comorbidities in the Brazilian population. METHODS: We performed a prospective analysis of a cohort of 1404 patients diagnosed with intracranial aneurysm admitted to the Hospital das Clinicas of the University of Sao Paulo, a referral hospital for the treatment of cerebrovascular diseases in Brazil. Patients admitted between September 2009 and September 2018 with radiological diagnosis of intracranial aneurysm were included in the study. RESULTS: A total of 2251 aneurysms were diagnosed. Females accounted for 1090 aneurysms (77.6%) and the mean age at diagnosis was 54.9 years (ranging 15–88). The most common location was middle cerebral artery (MCA) with 593 aneurysms (26.3%) followed by anterior cerebral artery (ACA) with 417 aneurysms (18.5%) and internal carotid artery in the posterior communicating segment with 405 aneurysms (18.0%). Males had higher rates of ACA aneurysms (29.7%) while females had higher rates of MCA aneurysms (26.1%). Sorting by size, 492 aneurysms were <5 mm (21.8%), 1524 measured 5–10 mm (67.7%), 119 size 11–24 mm (5.3%), and 116 were >24 mm (5.2%). The occurrence of multiple aneurysms was associated with female gender (P < 0.001) and smoking (P < 0.001), but not with hypertension (P = 0.121). CONCLUSION: In this population, the occurrence of intracranial aneurysm is related to several factors, including gender, age, smoking, and hypertension. Our study brought to light important characteristics of a large number of Brazilian patients regarding epidemiology, location, size, and multiplicity of intracranial aneurysms.
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spelling pubmed-69359672019-12-31 Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution Júnior, Jefferson Rosi Telles, João Paulo Mota da Silva, Saul Almeida Iglesio, Ricardo Ferrareto Brigido, Mauricio Mandel Pereira Caldas, José Guilherme Mendes Teixeira, Manoel Jacobsen Figueiredo, Eberval Gadelha Surg Neurol Int Original Article BACKGROUND: We sought to evaluate the epidemiology of intracranial aneurysms in relation to location, gender, age, presence of multiple aneurysms, and comorbidities in the Brazilian population. METHODS: We performed a prospective analysis of a cohort of 1404 patients diagnosed with intracranial aneurysm admitted to the Hospital das Clinicas of the University of Sao Paulo, a referral hospital for the treatment of cerebrovascular diseases in Brazil. Patients admitted between September 2009 and September 2018 with radiological diagnosis of intracranial aneurysm were included in the study. RESULTS: A total of 2251 aneurysms were diagnosed. Females accounted for 1090 aneurysms (77.6%) and the mean age at diagnosis was 54.9 years (ranging 15–88). The most common location was middle cerebral artery (MCA) with 593 aneurysms (26.3%) followed by anterior cerebral artery (ACA) with 417 aneurysms (18.5%) and internal carotid artery in the posterior communicating segment with 405 aneurysms (18.0%). Males had higher rates of ACA aneurysms (29.7%) while females had higher rates of MCA aneurysms (26.1%). Sorting by size, 492 aneurysms were <5 mm (21.8%), 1524 measured 5–10 mm (67.7%), 119 size 11–24 mm (5.3%), and 116 were >24 mm (5.2%). The occurrence of multiple aneurysms was associated with female gender (P < 0.001) and smoking (P < 0.001), but not with hypertension (P = 0.121). CONCLUSION: In this population, the occurrence of intracranial aneurysm is related to several factors, including gender, age, smoking, and hypertension. Our study brought to light important characteristics of a large number of Brazilian patients regarding epidemiology, location, size, and multiplicity of intracranial aneurysms. Scientific Scholar 2019-12-20 /pmc/articles/PMC6935967/ /pubmed/31893150 http://dx.doi.org/10.25259/SNI_443_2019 Text en Copyright: © 2019 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Júnior, Jefferson Rosi
Telles, João Paulo Mota
da Silva, Saul Almeida
Iglesio, Ricardo Ferrareto
Brigido, Mauricio Mandel
Pereira Caldas, José Guilherme Mendes
Teixeira, Manoel Jacobsen
Figueiredo, Eberval Gadelha
Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution
title Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution
title_full Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution
title_fullStr Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution
title_full_unstemmed Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution
title_short Epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single Brazilian institution
title_sort epidemiological analysis of 1404 patients with intracranial aneurysm followed in a single brazilian institution
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935967/
https://www.ncbi.nlm.nih.gov/pubmed/31893150
http://dx.doi.org/10.25259/SNI_443_2019
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