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Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells

BACKGROUND: Ticagrelor and clopidogrel, P2Y(12) receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in which inflammation is involved. Moreover, NF-B is the central regulator of i...

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Detalles Bibliográficos
Autores principales: Jia, Zhuyin, Huang, Yiwei, Ji, Xiaojun, Sun, Jiaju, Fu, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936058/
https://www.ncbi.nlm.nih.gov/pubmed/31888640
http://dx.doi.org/10.1186/s12872-019-01287-1