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MECoRank: cancer driver genes discovery simultaneously evaluating the impact of SNVs and differential expression on transcriptional networks
BACKGROUND: Although there are huge volumes of genomic data, how to decipher them and identify driver events is still a challenge. The current methods based on network typically use the relationship between genomic events and consequent changes in gene expression to nominate putative driver genes. B...
Autores principales: | Hui, Ying, Wei, Pi-Jing, Xia, Junfeng, Wang, Yu-Tian, Zheng, Chun-Hou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936061/ https://www.ncbi.nlm.nih.gov/pubmed/31888623 http://dx.doi.org/10.1186/s12920-019-0582-8 |
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