Exosomes derived from platelet-rich plasma present a novel potential in alleviating knee osteoarthritis by promoting proliferation and inhibiting apoptosis of chondrocyte via Wnt/β-catenin signaling pathway

BACKGROUND: Platelet-rich plasma (PRP) provides a nonsurgical approach for treating osteoarthritis (OA). Exosomes that play vital roles in intercellular communication have been studied extensively. Here, we investigated the therapeutic potential and molecular mechanism of exosomes derived from PRP (...

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Detalles Bibliográficos
Autores principales: Liu, Xuchang, Wang, Lubo, Ma, Chengshan, Wang, Guozong, Zhang, Yuanji, Sun, Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936129/
https://www.ncbi.nlm.nih.gov/pubmed/31888697
http://dx.doi.org/10.1186/s13018-019-1529-7

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