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normGAM: an R package to remove systematic biases in genome architecture mapping data

BACKGROUND: The genome architecture mapping (GAM) technique can capture genome-wide chromatin interactions. However, besides the known systematic biases in the raw GAM data, we have found a new type of systematic bias. It is necessary to develop and evaluate effective normalization methods to remove...

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Detalles Bibliográficos
Autores principales: Liu, Tong, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936146/
https://www.ncbi.nlm.nih.gov/pubmed/31888469
http://dx.doi.org/10.1186/s12864-019-6331-8