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normGAM: an R package to remove systematic biases in genome architecture mapping data
BACKGROUND: The genome architecture mapping (GAM) technique can capture genome-wide chromatin interactions. However, besides the known systematic biases in the raw GAM data, we have found a new type of systematic bias. It is necessary to develop and evaluate effective normalization methods to remove...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936146/ https://www.ncbi.nlm.nih.gov/pubmed/31888469 http://dx.doi.org/10.1186/s12864-019-6331-8 |