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PEIS: a novel approach of tumor purity estimation by identifying information sites through integrating signal based on DNA methylation data
BACKGROUND: Tumor purity plays an important role in understanding the pathogenic mechanism of tumors. The purity of tumor samples is highly sensitive to tumor heterogeneity. Due to Intratumoral heterogeneity of genetic and epigenetic data, it is suitable to study the purity of tumors. Among them, th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936156/ https://www.ncbi.nlm.nih.gov/pubmed/31888435 http://dx.doi.org/10.1186/s12859-019-3227-1 |