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Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry

AIM: The aim of the study is to investigate the photon beam perturbations induced by an in vivo diode in combination with prosthesis involvement in a human-like phantom. MATERIALS AND METHODS: Beam perturbations for 6 MV and 10 MV photons caused by an EDP-20(3G) in vivo diode in combination with pro...

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Autores principales: Ade, Nicholas, Eeden, Dete Van, Du Plessis, F. C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936197/
https://www.ncbi.nlm.nih.gov/pubmed/31908384
http://dx.doi.org/10.4103/jmp.JMP_59_19
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author Ade, Nicholas
Eeden, Dete Van
Du Plessis, F. C. P.
author_facet Ade, Nicholas
Eeden, Dete Van
Du Plessis, F. C. P.
author_sort Ade, Nicholas
collection PubMed
description AIM: The aim of the study is to investigate the photon beam perturbations induced by an in vivo diode in combination with prosthesis involvement in a human-like phantom. MATERIALS AND METHODS: Beam perturbations for 6 MV and 10 MV photons caused by an EDP-20(3G) in vivo diode in combination with prosthesis involvement were studied in a unique water-equivalent pelvic phantom, equipped with bony structures and Ti prosthesis using single fields between 2 × 2 and 15 cm × 15 cm as well as 10 MV lateral opposing fields and a four-field plan. Dose distributions were measured with Gafchromic EBT3 films with and without the diode included in the beams on the prosthesis (prosthetic fields) and non-prosthesis (non-prosthetic fields) sides of the phantom. Differences between prosthetic and non-prosthetic field dose data were determined to assess the effect of the prosthesis on the diode-induced beam perturbations inside the phantom. RESULTS: Photon beam dose perturbations ranged from 2% to 7% and from 5% to 12% for prosthetic and non-prosthetic fields, respectively, with relative differences between 2% and 4%. In addition, d(50) depths ranging from 8.7 to 11.5 cm and from 11.5 to 15 cm were acquired in the phantom for prosthetic and non-prosthetic fields, respectively, with relative differences between 2% and 5%. CONCLUSION: On the basis of accuracy requirements in radiotherapy noting that a small underdose to tumors could yield a decrease in the probability of tumor control, the diode-induced beam perturbations in combination with prosthesis involvement in the photon fields may affect treatment outcome, as there would be a reduction in the prescribed target dose during treatment delivery.
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spelling pubmed-69361972020-01-06 Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry Ade, Nicholas Eeden, Dete Van Du Plessis, F. C. P. J Med Phys Original Article AIM: The aim of the study is to investigate the photon beam perturbations induced by an in vivo diode in combination with prosthesis involvement in a human-like phantom. MATERIALS AND METHODS: Beam perturbations for 6 MV and 10 MV photons caused by an EDP-20(3G) in vivo diode in combination with prosthesis involvement were studied in a unique water-equivalent pelvic phantom, equipped with bony structures and Ti prosthesis using single fields between 2 × 2 and 15 cm × 15 cm as well as 10 MV lateral opposing fields and a four-field plan. Dose distributions were measured with Gafchromic EBT3 films with and without the diode included in the beams on the prosthesis (prosthetic fields) and non-prosthesis (non-prosthetic fields) sides of the phantom. Differences between prosthetic and non-prosthetic field dose data were determined to assess the effect of the prosthesis on the diode-induced beam perturbations inside the phantom. RESULTS: Photon beam dose perturbations ranged from 2% to 7% and from 5% to 12% for prosthetic and non-prosthetic fields, respectively, with relative differences between 2% and 4%. In addition, d(50) depths ranging from 8.7 to 11.5 cm and from 11.5 to 15 cm were acquired in the phantom for prosthetic and non-prosthetic fields, respectively, with relative differences between 2% and 5%. CONCLUSION: On the basis of accuracy requirements in radiotherapy noting that a small underdose to tumors could yield a decrease in the probability of tumor control, the diode-induced beam perturbations in combination with prosthesis involvement in the photon fields may affect treatment outcome, as there would be a reduction in the prescribed target dose during treatment delivery. Wolters Kluwer - Medknow 2019 2019-12-11 /pmc/articles/PMC6936197/ /pubmed/31908384 http://dx.doi.org/10.4103/jmp.JMP_59_19 Text en Copyright: © 2019 Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Ade, Nicholas
Eeden, Dete Van
Du Plessis, F. C. P.
Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry
title Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry
title_full Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry
title_fullStr Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry
title_full_unstemmed Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry
title_short Dose Shadowing and Prosthesis Involvement for Megavoltage Photon In vivo Diode Dosimetry
title_sort dose shadowing and prosthesis involvement for megavoltage photon in vivo diode dosimetry
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936197/
https://www.ncbi.nlm.nih.gov/pubmed/31908384
http://dx.doi.org/10.4103/jmp.JMP_59_19
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