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Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation

OBJECTIVE: The aim of the present study is to experimentally measure the radial dose function g(r) and anisotropy function F(r,θ) of GammaMed Plus (192)Ir high-dose-rate source in a bounded water phantom using thermoluminescent dosimeter (TLD) and film dosimetry and compare the obtained results with...

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Autores principales: Buchapudi, Rekha Reddy, Manickam, Ravikumar, Chandaraj, Varatharaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936200/
https://www.ncbi.nlm.nih.gov/pubmed/31908383
http://dx.doi.org/10.4103/jmp.JMP_60_19
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author Buchapudi, Rekha Reddy
Manickam, Ravikumar
Chandaraj, Varatharaj
author_facet Buchapudi, Rekha Reddy
Manickam, Ravikumar
Chandaraj, Varatharaj
author_sort Buchapudi, Rekha Reddy
collection PubMed
description OBJECTIVE: The aim of the present study is to experimentally measure the radial dose function g(r) and anisotropy function F(r,θ) of GammaMed Plus (192)Ir high-dose-rate source in a bounded water phantom using thermoluminescent dosimeter (TLD) and film dosimetry and compare the obtained results with egs_brachy Monte Carlo (MC)-calculated values for the same geometry. MATERIALS AND METHODS: The recently developed egs_brachy is a fast Electron Gamma Shower National Research Council of Canada MC application which is intended for brachytherapy applications. The dosimetric dataset recommended by Task Group 43 update (TG43U1) is calculated using egs_brachy for an unbounded phantom. Subsequently, radial dose function g(r) and anisotropy function F(r,θ) are measured experimentally in a bounded water phantom using TLD-100 and Gafchromic EBT2 film. RESULTS: The TG43U1 dosimetric parameters were determined using the egs_brachy MC calculation and compared with published data which are found to be in good agreement within 2%. The experimentally measured g(r) and F(r,θ) and its egs_brachy MC code-calculated values for a bounded phantom geometry are found to be good in agreement within the acceptable experimental uncertainties of 3%. CONCLUSION: Our experimental phantom size represents the average patient width of 30 cm; hence, results are closer to scattering conditions in clinical situations. The experimentally measured g(r) and F(r,θ) and egs_brachy MC calculations for bounded geometry are well in agreement within experimental uncertainties. Further, the confidence level of our comparative study is enhanced by validating the egs_brachy MC code for the unbounded phantom with respect to consensus data.
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spelling pubmed-69362002020-01-06 Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation Buchapudi, Rekha Reddy Manickam, Ravikumar Chandaraj, Varatharaj J Med Phys Original Article OBJECTIVE: The aim of the present study is to experimentally measure the radial dose function g(r) and anisotropy function F(r,θ) of GammaMed Plus (192)Ir high-dose-rate source in a bounded water phantom using thermoluminescent dosimeter (TLD) and film dosimetry and compare the obtained results with egs_brachy Monte Carlo (MC)-calculated values for the same geometry. MATERIALS AND METHODS: The recently developed egs_brachy is a fast Electron Gamma Shower National Research Council of Canada MC application which is intended for brachytherapy applications. The dosimetric dataset recommended by Task Group 43 update (TG43U1) is calculated using egs_brachy for an unbounded phantom. Subsequently, radial dose function g(r) and anisotropy function F(r,θ) are measured experimentally in a bounded water phantom using TLD-100 and Gafchromic EBT2 film. RESULTS: The TG43U1 dosimetric parameters were determined using the egs_brachy MC calculation and compared with published data which are found to be in good agreement within 2%. The experimentally measured g(r) and F(r,θ) and its egs_brachy MC code-calculated values for a bounded phantom geometry are found to be good in agreement within the acceptable experimental uncertainties of 3%. CONCLUSION: Our experimental phantom size represents the average patient width of 30 cm; hence, results are closer to scattering conditions in clinical situations. The experimentally measured g(r) and F(r,θ) and egs_brachy MC calculations for bounded geometry are well in agreement within experimental uncertainties. Further, the confidence level of our comparative study is enhanced by validating the egs_brachy MC code for the unbounded phantom with respect to consensus data. Wolters Kluwer - Medknow 2019 2019-12-11 /pmc/articles/PMC6936200/ /pubmed/31908383 http://dx.doi.org/10.4103/jmp.JMP_60_19 Text en Copyright: © 2019 Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Buchapudi, Rekha Reddy
Manickam, Ravikumar
Chandaraj, Varatharaj
Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation
title Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation
title_full Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation
title_fullStr Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation
title_full_unstemmed Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation
title_short Experimental Determination of Radial Dose Function and Anisotropy Function of GammaMed Plus (192)Ir High-Dose-Rate Brachytherapy Source in a Bounded Water Phantom and its Comparison with egs_brachy Monte Carlo Simulation
title_sort experimental determination of radial dose function and anisotropy function of gammamed plus (192)ir high-dose-rate brachytherapy source in a bounded water phantom and its comparison with egs_brachy monte carlo simulation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936200/
https://www.ncbi.nlm.nih.gov/pubmed/31908383
http://dx.doi.org/10.4103/jmp.JMP_60_19
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