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Identification of a novel regulatory pathway for PPARα by RNA-seq characterization of the endothelial cell lipid peroxidative injury transcriptome

Endothelial dysfunction caused by endothelial cell injuries is the initiating factor for atherosclerosis (AS), and lipid peroxidative injury is one of a dominant factor for AS pathogenesis. Using RNA-seq, we compared changes in transcriptome expression before and after endothelial cell injury, and f...

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Detalles Bibliográficos
Autores principales: Dou, Fangfang, Wu, Beiling, Sun, Lin, Chen, Jiulin, Liu, Te, Yu, Zhihua, Chen, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936254/
https://www.ncbi.nlm.nih.gov/pubmed/31847785
http://dx.doi.org/10.1098/rsob.190141