Cargando…

Combined Use of Astragalus Polysaccharide and Berberine Attenuates Insulin Resistance in IR-HepG2 Cells via Regulation of the Gluconeogenesis Signaling Pathway

Insulin resistance (IR) is likely to induce metabolic syndrome and type 2 diabetes mellitus (T2DM). Gluconeogenesis (GNG) is a complex metabolic process that may result in glucose generation from certain non-carbohydrate substrates. Chinese herbal medicine astragalus polysaccharides and berberine ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Zhu-Jun, Lin, Min, Zhang, Xin, Qin, Lu-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936338/ https://www.ncbi.nlm.nih.gov/pubmed/31920677 http://dx.doi.org/10.3389/fphar.2019.01508

Ejemplares similares

Berberine Improves Glucose and Lipid Metabolism in HepG2 Cells Through AMPKα1 Activation
por: Ren, Gang, et al.
Publicado: (2020)

Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF‐1 pathway
por: Yue, Xinxin, et al.
Publicado: (2023)

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
por: Grünig, David, et al.
Publicado: (2018)

Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2
por: Xiahou, Zhikai, et al.
Publicado: (2022)

Resveratrol metabolites ameliorate insulin resistance in HepG2 hepatocytes by modulating IRS-1/AMPK
por: Teng, Wendi, et al.
Publicado: (2018)

A Review of the Pharmacological Action of Astragalus Polysaccharide
por: Zheng, Yijun, et al.
Publicado: (2020)

Induction of Apoptosis by Berberine in Hepatocellular Carcinoma HepG2 Cells via Downregulation of NF-κB
por: Li, Min, et al.
Publicado: (2017)

RASAL1 inhibits HepG2 cell growth via HIF-2α mediated gluconeogenesis
por: Meng, Fanhua, et al.
Publicado: (2017)

Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes
por: Zhang, Yi, et al.
Publicado: (2020)

Berberine Attenuates Development of the Hepatic Gluconeogenesis and Lipid Metabolism Disorder in Type 2 Diabetic Mice and in Palmitate-Incubated HepG2 Cells through Suppression of the HNF-4α miR122 Pathway
por: Wei, Shengnan, et al.
Publicado: (2016)

Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
por: Yu, Rong, et al.
Publicado: (2014)

Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells
por: Li, Qiao, et al.
Publicado: (2019)

Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation
por: Wang, Chunyi, et al.
Publicado: (2018)

Oleanolic Acid Attenuates Insulin Resistance via NF-κB to Regulate the IRS1-GLUT4 Pathway in HepG2 Cells
por: Li, Ming, et al.
Publicado: (2015)

Hemicellulosic Polysaccharides From Bamboo Leaves Promoted by Phosphotungstic Acids and Its Attenuation of Oxidative Stress in HepG2 Cells
por: Xiao, Zhuqian, et al.
Publicado: (2022)

Lycorine Induces Mitochondria-Dependent Apoptosis in Hepatoblastoma HepG2 Cells Through ROCK1 Activation
por: Liu, Wu-yi, et al.
Publicado: (2019)

A proteomic analysis of mushroom polysaccharide-treated HepG2 cells
por: Chai, Yangyang, et al.
Publicado: (2016)

Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells
por: Zhang, Ji, et al.
Publicado: (2019)

The Current Application and Future Prospects of Astragalus Polysaccharide Combined With Cancer Immunotherapy: A Review
por: Kong, Fanming, et al.
Publicado: (2021)

High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells
por: Rondón-Ortiz, Alejandro N., et al.
Publicado: (2017)

Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis
por: Bao, Wan-Rong, et al.
Publicado: (2019)

Hepatoprotective Effect of Steroidal Glycosides From Dioscorea villosa on Hydrogen Peroxide-Induced Hepatotoxicity in HepG2 Cells
por: Siddiqui, Maqsood A., et al.
Publicado: (2018)

A Novel Indolizine Derivative Induces Apoptosis Through the Mitochondria p53 Pathway in HepG2 Cells
por: Liu, Yushuang, et al.
Publicado: (2019)

Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics
por: Wang, Saisai, et al.
Publicado: (2020)

Sargassum fusiforme polysaccharide attenuates high‐sugar–induced lipid accumulation in HepG2 cells and Drosophila melanogaster larvae
por: He, Dan, et al.
Publicado: (2021)

The idiosyncratic drug-induced gene expression changes in HepG2 cells
por: Jiang, J., et al.
Publicado: (2017)

Cerebral Gluconeogenesis and Diseases
por: Yip, James, et al.
Publicado: (2017)

A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats
por: Ansari, AbuZar, et al.
Publicado: (2018)

Synthesis of Chalcone Derivatives: Inducing Apoptosis of HepG2 Cells via Regulating Reactive Oxygen Species and Mitochondrial Pathway
por: Zhu, Hongtian, et al.
Publicado: (2019)

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction
por: Jiang, Linhai, et al.
Publicado: (2021)

Combination Treatment of Deep Sea Water and Fucoidan Attenuates High Glucose-Induced Insulin-Resistance in HepG2 Hepatocytes
por: He, Shan, et al.
Publicado: (2018)

Pharmacological Effects and Molecular Protective Mechanisms of Astragalus Polysaccharides on Nonalcoholic Fatty Liver Disease
por: Zhang, Jing, et al.
Publicado: (2022)

WTAP mediates the anti-inflammatory effect of Astragalus mongholicus polysaccharide on THP-1 macrophages
por: Long, Haijiao, et al.
Publicado: (2022)

Gut microbiota mediated hypoglycemic effect of Astragalus membranaceus polysaccharides in db/db mice
por: Song, Qianbo, et al.
Publicado: (2022)

The Compound of Mangiferin-Berberine Salt Has Potent Activities in Modulating Lipid and Glucose Metabolisms in HepG2 Cells
por: Wang, Can, et al.
Publicado: (2016)

Astragalus Polysaccharide Reduces Blood Pressure, Renal Damage, and Dysfunction Through the TGF-β1-ILK Pathway
por: Zheng, Wei, et al.
Publicado: (2021)

The Mechanism by Which Amentoflavone Improves Insulin Resistance in HepG2 Cells
por: Zheng, Xiaoke, et al.
Publicado: (2016)

Scallop mantle extract inhibits insulin signaling in HepG2 cells
por: Kariya, Takahide, et al.
Publicado: (2019)

Ultrasonic-Cellulase Synergistic Extraction of Crude Polysaccharides from Moringa oleifera Leaves and Alleviation of Insulin Resistance in HepG2 Cells
por: Gu, Fan, et al.
Publicado: (2022)

Theabrownin from Dark Tea Ameliorates Insulin Resistance via Attenuating Oxidative Stress and Modulating IRS-1/PI3K/Akt Pathway in HepG2 Cells
por: Liu, Jia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7a0fisrfd4omutucupktpl11ov