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Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies

INTRODUCTION: The pathophysiology of preeclampsia is largely unknown. Serum placental induced growth factor (PlGF) levels are decreased during second trimester pregnancy. Aberrant DNA methylation is suggested to be involved in the etiology of preeclampsia (PE). We hypothesize that DNA methylation is...

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Detalles Bibliográficos
Autores principales:	Heil, Sandra G., Herzog, Emilie M., Griffioen, Pieter H., van Zelst, Bertrand, Willemsen, Sten P., de Rijke, Yolanda B., Steegers-Theunissen, Regine P. M., Steegers, Eric A. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936822/ https://www.ncbi.nlm.nih.gov/pubmed/31887212 http://dx.doi.org/10.1371/journal.pone.0226969

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