Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans

Viral glycoproteins are a primary target for host antibody responses. However, glycans on viral glycoproteins can hinder antibody recognition since they are self glycans derived from the host biosynthesis pathway. During natural HIV-1 infection, neutralizing antibodies are made against glycans on HI...

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Detalles Bibliográficos
Autores principales: Wu, Nelson R., Nicely, Nathan I., Lee, Esther M., Reed, Rachel K., Watts, Brian E., Cai, Fangping, Walkowicz, William E., Aussedat, Baptiste, Jones, Julia A., Eaton, Amanda, Trama, Ashley M., Alam, S. Munir, Montefiori, David C., Haynes, Barton F., Saunders, Kevin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936856/
https://www.ncbi.nlm.nih.gov/pubmed/31841553
http://dx.doi.org/10.1371/journal.ppat.1008165

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