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Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI

OBJECTIVE: Monocyte to high-density lipoprotein ratio (MHR) has recently been postulated as a novel parameter related to adverse cardiovascular outcomes. In this study, we aimed to investigate the correlation of MHR with stent restenosis (SR) rates after the primary percutaneous coronary interventio...

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Autores principales: Avci, Ilhan Ilker, Sahin, Irfan, Gungor, Baris, Karatas, Mehmet Baran, Ozcan, Kazim Serhan, Canga, Yigit, Keskin, Muhammet, Hayiroglu, Mert Ilker, Karadeniz, Fatma Ozpamuk, Sungur, Aylin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936946/
https://www.ncbi.nlm.nih.gov/pubmed/31909386
http://dx.doi.org/10.14744/nci.2018.93653
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author Avci, Ilhan Ilker
Sahin, Irfan
Gungor, Baris
Karatas, Mehmet Baran
Ozcan, Kazim Serhan
Canga, Yigit
Keskin, Muhammet
Hayiroglu, Mert Ilker
Karadeniz, Fatma Ozpamuk
Sungur, Aylin
author_facet Avci, Ilhan Ilker
Sahin, Irfan
Gungor, Baris
Karatas, Mehmet Baran
Ozcan, Kazim Serhan
Canga, Yigit
Keskin, Muhammet
Hayiroglu, Mert Ilker
Karadeniz, Fatma Ozpamuk
Sungur, Aylin
author_sort Avci, Ilhan Ilker
collection PubMed
description OBJECTIVE: Monocyte to high-density lipoprotein ratio (MHR) has recently been postulated as a novel parameter related to adverse cardiovascular outcomes. In this study, we aimed to investigate the correlation of MHR with stent restenosis (SR) rates after the primary percutaneous coronary intervention (PCI) and bare-metal stent (BMS) implantation. METHODS: In this study, patients who had undergone primary PCI for STEMI and had a control angiogram during follow-up were retrospectively recruited. Patients were categorized according to admission MHR tertiles, clinical and angiographic data were compared. In addition, predictors of SR were evaluated with logistic regression analysis. RESULTS: A total number of 448 patients (240 patients with SR and 208 patients without SR) were included in this study. Patients were categorized into three groups according to tertiles of admission MHR. During a follow-up period of median 12 months, the rate of SR was significantly higher in patients with higher MHR levels (45% in tertile 1, 54% in tertile 2 and 62% in tertile 3, p<0.01). In multivariate Cox regression analysis, male gender, stent length, admission NLR levels and MHR levels (HR 1.03, 95% CI 1.02–1.06, p<0.01) remained as the independent predictors of SR in the study population. CONCLUSION: Gender, stent length, higher MHR and NLR levels are correlated to SR after primary PCI.
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spelling pubmed-69369462020-01-06 Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI Avci, Ilhan Ilker Sahin, Irfan Gungor, Baris Karatas, Mehmet Baran Ozcan, Kazim Serhan Canga, Yigit Keskin, Muhammet Hayiroglu, Mert Ilker Karadeniz, Fatma Ozpamuk Sungur, Aylin North Clin Istanb Original Article OBJECTIVE: Monocyte to high-density lipoprotein ratio (MHR) has recently been postulated as a novel parameter related to adverse cardiovascular outcomes. In this study, we aimed to investigate the correlation of MHR with stent restenosis (SR) rates after the primary percutaneous coronary intervention (PCI) and bare-metal stent (BMS) implantation. METHODS: In this study, patients who had undergone primary PCI for STEMI and had a control angiogram during follow-up were retrospectively recruited. Patients were categorized according to admission MHR tertiles, clinical and angiographic data were compared. In addition, predictors of SR were evaluated with logistic regression analysis. RESULTS: A total number of 448 patients (240 patients with SR and 208 patients without SR) were included in this study. Patients were categorized into three groups according to tertiles of admission MHR. During a follow-up period of median 12 months, the rate of SR was significantly higher in patients with higher MHR levels (45% in tertile 1, 54% in tertile 2 and 62% in tertile 3, p<0.01). In multivariate Cox regression analysis, male gender, stent length, admission NLR levels and MHR levels (HR 1.03, 95% CI 1.02–1.06, p<0.01) remained as the independent predictors of SR in the study population. CONCLUSION: Gender, stent length, higher MHR and NLR levels are correlated to SR after primary PCI. Kare Publishing 2018-12-21 /pmc/articles/PMC6936946/ /pubmed/31909386 http://dx.doi.org/10.14744/nci.2018.93653 Text en Copyright: © 2019 by Istanbul Northern Anatolian Association of Public Hospitals http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Original Article
Avci, Ilhan Ilker
Sahin, Irfan
Gungor, Baris
Karatas, Mehmet Baran
Ozcan, Kazim Serhan
Canga, Yigit
Keskin, Muhammet
Hayiroglu, Mert Ilker
Karadeniz, Fatma Ozpamuk
Sungur, Aylin
Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI
title Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI
title_full Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI
title_fullStr Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI
title_full_unstemmed Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI
title_short Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI
title_sort association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in stemi patients treated with primary pci
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936946/
https://www.ncbi.nlm.nih.gov/pubmed/31909386
http://dx.doi.org/10.14744/nci.2018.93653
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