Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1

Radiotherapy induces immune-related responses in cancer patients by various mechanisms. Here, we investigate the immunomodulatory role of tumor-derived microparticles (TMPs)—extracellular vesicles shed from tumor cells—following radiotherapy. We demonstrate that breast carcinoma cells exposed to rad...

Descripción completa

Detalles Bibliográficos
Autores principales: Timaner, Michael, Kotsofruk, Ruslana, Raviv, Ziv, Magidey, Ksenia, Shechter, Dvir, Kan, Tal, Nevelsky, Alexander, Daniel, Shahar, de Vries, Elisabeth G. E., Zhang, Tongwu, Kaidar-Person, Orit, Kerbel, Robert S., Shaked, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937213/
https://www.ncbi.nlm.nih.gov/pubmed/31467431
http://dx.doi.org/10.1038/s41388-019-0971-7

Ejemplares similares

Ejemplares similares