Cargando…
Sustained discontinuation of infliximab with a raising-dose strategy after obtaining remission in patients with rheumatoid arthritis: the RRRR study, a randomised controlled trial
OBJECTIVES: The aim of this study is to determine whether the ‘programmed’ infliximab (IFX) treatment strategy (for which the dose of IFX was adjusted based on the baseline serum tumour necrosis factor α (TNF-α)) is beneficial to induction of clinical remission after 54 weeks and sustained discontin...
Autores principales: | Tanaka, Yoshiya, Oba, Koji, Koike, Takao, Miyasaka, Nobuyuki, Mimori, Tsuneyo, Takeuchi, Tsutomu, Hirata, Shintaro, Tanaka, Eiichi, Yasuoka, Hidekata, Kaneko, Yuko, Murakami, Kosaku, Koga, Tomohiro, Nakano, Kazuhisa, Amano, Koichi, Ushio, Kazuyasu, Atsumi, Tatsuya, Inoo, Masayuki, Hatta, Kazuhiro, Mizuki, Shinichi, Nagaoka, Shouhei, Tsunoda, Shinichiro, Dobashi, Hiroaki, Horie, Nao, Sato, Norihiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937411/ https://www.ncbi.nlm.nih.gov/pubmed/31630117 http://dx.doi.org/10.1136/annrheumdis-2019-216169 |
Ejemplares similares
-
Remission induction by Raising the dose of Remicade in RA (RRRR) study: Rationale and study protocol for a randomized controlled trial comparing for sustained clinical remission after discontinuation of infliximab in patients with rheumatoid arthritis
por: Oba, Koji, et al.
Publicado: (2017) -
Adalimumab discontinuation in patients with early rheumatoid arthritis who were initially treated with methotrexate alone or in combination with adalimumab: 1 year outcomes of the HOPEFUL-2 study
por: Tanaka, Yoshiya, et al.
Publicado: (2016) -
Association of a FAM13A variant with interstitial lung disease in Japanese rheumatoid arthritis
por: Higuchi, Takashi, et al.
Publicado: (2023) -
Irreversible covalent Bruton’s tyrosine kinase inhibitor, TAS5315 versus placebo in rheumatoid arthritis patients with inadequate response to methotrexate: a randomised, double-blind, phase IIa trial
por: Takeuchi, Tsutomu, et al.
Publicado: (2023) -
Randomised, double-blind, phase III study comparing the infliximab biosimilar, PF-06438179/GP1111, with reference infliximab: efficacy, safety and immunogenicity from week 30 to week 54
por: Alten, Rieke, et al.
Publicado: (2019)