Combining SPR with atomic-force microscopy enables single-molecule insights into activation and suppression of the complement cascade

Activation and suppression of the complement system compete on every serum-exposed surface, host or foreign. Potentially harmful outcomes of this competition depend on surface molecules through mechanisms that remain incompletely understood. Combining surface plasmon resonance (SPR) with atomic forc...

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Detalles Bibliográficos
Autores principales: Makou, Elisavet, Bailey, Richard G., Johnston, Heather, Parkin, John D., Hulme, Alison N., Hähner, Georg, Barlow, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937562/
https://www.ncbi.nlm.nih.gov/pubmed/31719147
http://dx.doi.org/10.1074/jbc.RA119.010913

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