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TOPK promotes metastasis of esophageal squamous cell carcinoma by activating the Src/GSK3β/STAT3 signaling pathway via γ-catenin

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a fatal disease with poor prognosis. The predominant reason for ESCC-related death is distal metastasis. A comprehensive understanding of the molecular mechanism underlying metastasis is needed for improving patient prognosis. T-LAK cell-origi...

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Detalles Bibliográficos
Autores principales: Jiang, Yanan, Zhang, Jing, Zhao, Jimin, Li, Zhenzhen, Chen, Hanyong, Qiao, Yan, Chen, Xinhuan, Liu, Kangdong, Dong, Ziming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937732/
https://www.ncbi.nlm.nih.gov/pubmed/31888532
http://dx.doi.org/10.1186/s12885-019-6453-z