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ZDOG: zooming in on dominating genes with mutations in cancer pathways
BACKGROUND: Inference of cancer-causing genes and their biological functions are crucial but challenging due to the heterogeneity of somatic mutations. The heterogeneity of somatic mutations reveals that only a handful of oncogenes mutate frequently and a number of cancer-causing genes mutate rarely...
Autores principales: | Alberts, Rudi, Chen, Jinyu, Zhang, Louxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937862/ https://www.ncbi.nlm.nih.gov/pubmed/31888434 http://dx.doi.org/10.1186/s12859-019-3326-z |
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