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APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

BACKGROUND: The application of advanced sequencing technologies and improved mass-spectrometry platforms revealed significant changes in gene expression and lipids in Alzheimer’s disease (AD) brain. The results so far have prompted further research using “multi-omics” approaches. These approaches be...

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Detalles Bibliográficos
Autores principales: Lefterov, Iliya, Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Letronne, Florent, Biedrzycki, Richard J., Kofler, Julia, Han, Xianlin, Wang, Jianing, Schug, Jonathan, Koldamova, Radosveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937981/
https://www.ncbi.nlm.nih.gov/pubmed/31888770
http://dx.doi.org/10.1186/s13195-019-0558-0