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Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador

OBJECTIVE. Evaluate the control of pulmonary tuberculosis in a detention center and identify the risk factors associated with unsuccessful treatment in the largest prison in Ecuador. METHODS. Surveillance data from the prison and a cohort of inmates diagnosed with tuberculosis (TB) between 2015 and...

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Autores principales: Chong, Félix, Marín, Diana, Pérez, Freddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Organización Panamericana de la Salud 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938213/
https://www.ncbi.nlm.nih.gov/pubmed/31908648
http://dx.doi.org/10.26633/RPSP.2019.106
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author Chong, Félix
Marín, Diana
Pérez, Freddy
author_facet Chong, Félix
Marín, Diana
Pérez, Freddy
author_sort Chong, Félix
collection PubMed
description OBJECTIVE. Evaluate the control of pulmonary tuberculosis in a detention center and identify the risk factors associated with unsuccessful treatment in the largest prison in Ecuador. METHODS. Surveillance data from the prison and a cohort of inmates diagnosed with tuberculosis (TB) between 2015 and 2016 were analyzed. Records without treatment outcome information were excluded. The percentage of patients with respiratory symptoms and TB incidence rate were estimated. Factors associated with unsuccessful treatment were estimated with binomial logistic regression. RESULTS. Of 59 846 medical consultations, 3% of respiratory symptoms were identified and, of these, 326 inmates had TB; 184 of them were analyzed. The incidence rate of TB in the prison was 3 947/100 000 inhabitants. Treatment was successful in 70.4% (65.6% cured; 4.8% treatment completed) and unsuccessful in 29.4% (12.5% lost during follow-up, 5% deceased, 1.1% treatment failure, 10.8% not evaluated). Seropositivity for human immunodeficiency virus (HIV) was associated with an increased risk of unsuccessful treatment (relative risk: 1.66, 95% confidence interval: 1.33-2.07). CONCLUSION. The incidence of TB in the prison was 123 times higher than in the general population of Ecuador. Prisoners co-infected with HIV-TB are at greater risk of not having a successful treatment, and articulation is required between the ministries of health and justice that allows the proper implementation of health protocols and the End TB Strategy.
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spelling pubmed-69382132020-01-06 Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador Chong, Félix Marín, Diana Pérez, Freddy Rev Panam Salud Publica Investigación Original OBJECTIVE. Evaluate the control of pulmonary tuberculosis in a detention center and identify the risk factors associated with unsuccessful treatment in the largest prison in Ecuador. METHODS. Surveillance data from the prison and a cohort of inmates diagnosed with tuberculosis (TB) between 2015 and 2016 were analyzed. Records without treatment outcome information were excluded. The percentage of patients with respiratory symptoms and TB incidence rate were estimated. Factors associated with unsuccessful treatment were estimated with binomial logistic regression. RESULTS. Of 59 846 medical consultations, 3% of respiratory symptoms were identified and, of these, 326 inmates had TB; 184 of them were analyzed. The incidence rate of TB in the prison was 3 947/100 000 inhabitants. Treatment was successful in 70.4% (65.6% cured; 4.8% treatment completed) and unsuccessful in 29.4% (12.5% lost during follow-up, 5% deceased, 1.1% treatment failure, 10.8% not evaluated). Seropositivity for human immunodeficiency virus (HIV) was associated with an increased risk of unsuccessful treatment (relative risk: 1.66, 95% confidence interval: 1.33-2.07). CONCLUSION. The incidence of TB in the prison was 123 times higher than in the general population of Ecuador. Prisoners co-infected with HIV-TB are at greater risk of not having a successful treatment, and articulation is required between the ministries of health and justice that allows the proper implementation of health protocols and the End TB Strategy. Organización Panamericana de la Salud 2019-12-30 /pmc/articles/PMC6938213/ /pubmed/31908648 http://dx.doi.org/10.26633/RPSP.2019.106 Text en https://creativecommons.org/licenses/by/4.0/ Este es un artículo de acceso abierto distribuido bajo los términos de la licencia Creative Commons Attribution-NonCommercial-NoDerivs 3.0 IGO, que permite su uso, distribución y reproducción en cualquier medio, siempre que el trabajo original se cite de la manera adecuada. No se permiten modificaciones a los artículos ni su uso comercial. Al reproducir un artículo no debe haber ningún indicio de que la OPS o el artículo avalan a una organización o un producto específico. El uso del logo de la OPS no está permitido. Esta leyenda debe conservarse, junto con la URL original del artículo.
spellingShingle Investigación Original
Chong, Félix
Marín, Diana
Pérez, Freddy
Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador
title Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador
title_full Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador
title_fullStr Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador
title_full_unstemmed Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador
title_short Baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de Ecuador
title_sort baja captación y éxito en el tratamiento para la tuberculosis en una cárcel de ecuador
topic Investigación Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938213/
https://www.ncbi.nlm.nih.gov/pubmed/31908648
http://dx.doi.org/10.26633/RPSP.2019.106
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