Safe and effective subcutaneous adipolysis in minipigs by a collagenase derivative

Adipocytes attached to the extracellular matrix (ECM) mainly consist of collagen in adipose tissues, while the degradation of ECM by collagenase induces the apoptosis of adipocytes, leading to a decrease in local subcutaneous adipose. To achieve this goal, we are developing a mutant collagenase H (C...

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Detalles Bibliográficos
Autores principales: Chen, Fuding, Du, Gang, Shih, Meishu, Yuan, Hongjiang, Bao, Peng, Shi, Sheng, Cang, Yong, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938318/
https://www.ncbi.nlm.nih.gov/pubmed/31891643
http://dx.doi.org/10.1371/journal.pone.0227202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938318/
https://www.ncbi.nlm.nih.gov/pubmed/31891643
http://dx.doi.org/10.1371/journal.pone.0227202

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