Longitudinal monitoring of KRAS-mutated circulating tumor DNA enables the prediction of prognosis and therapeutic responses in patients with pancreatic cancer

BACKGROUND: Liquid biopsies enable the detection of circulating tumor DNA (ctDNA). However, the clinical significance of KRAS-mutated ctDNA for pancreatic cancer has been inconsistent with respect to its prognostic and predictive potential. METHODS AND FINDINGS: A total of 422 blood samples were col...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Fumiaki, Suzuki, Koichi, Tamaki, Sawako, Abe, Iku, Endo, Yuhei, Takayama, Yuji, Ishikawa, Hideki, Kakizawa, Nao, Saito, Masaaki, Futsuhara, Kazushige, Noda, Hiroshi, Konishi, Fumio, Rikiyama, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938323/
https://www.ncbi.nlm.nih.gov/pubmed/31891652
http://dx.doi.org/10.1371/journal.pone.0227366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938323/
https://www.ncbi.nlm.nih.gov/pubmed/31891652
http://dx.doi.org/10.1371/journal.pone.0227366

Ejemplares similares