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Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants
BACKGROUND: A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional abilities including classical complement pathway inhibition, myeloperoxidase inhibition, NET inhibition and antioxidant activity. PA-dPEG24 is composed of a se...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938345/ https://www.ncbi.nlm.nih.gov/pubmed/31891617 http://dx.doi.org/10.1371/journal.pone.0226875 |