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Hypofibrinolysis induced by tranexamic acid does not influence inflammation and mortality in a polymicrobial sepsis model

The biological relevance of fibrinolysis to the host response to sepsis is illustrated by pathogens such as S. pyogenes and Y. pestis, whose virulence factors are proteins that challenge the balance between pro- and anti-fibrinolytic factors of the host, and by the consistent finding of hypofibrinol...

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Detalles Bibliográficos
Autores principales: Campos Nogueira, Yzabella Alves, Gomes da Costa, Loredana Nilkenes, Levy, Carlos Emilio, Orsi, Fernanda Andrade, de Lima, Franciele, Annichinno-Bizzacchi, Joyce M., De Paula, Erich Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938370/
https://www.ncbi.nlm.nih.gov/pubmed/31891611
http://dx.doi.org/10.1371/journal.pone.0226871