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Hypofibrinolysis induced by tranexamic acid does not influence inflammation and mortality in a polymicrobial sepsis model
The biological relevance of fibrinolysis to the host response to sepsis is illustrated by pathogens such as S. pyogenes and Y. pestis, whose virulence factors are proteins that challenge the balance between pro- and anti-fibrinolytic factors of the host, and by the consistent finding of hypofibrinol...
Autores principales: | Campos Nogueira, Yzabella Alves, Gomes da Costa, Loredana Nilkenes, Levy, Carlos Emilio, Orsi, Fernanda Andrade, de Lima, Franciele, Annichinno-Bizzacchi, Joyce M., De Paula, Erich Vinicius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938370/ https://www.ncbi.nlm.nih.gov/pubmed/31891611 http://dx.doi.org/10.1371/journal.pone.0226871 |
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