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Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation

Introduction Vascularized composite allotransplantation (VCA) has added another step to the reconstructive ladder, leading to a paradigm shift in the approach toward management of cases of upper limb amputations. In this article, we discuss in detail the technical aspects of proximal forearm level t...

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Autores principales: Sharma, Mohit, Iyer, Subramania, Purushottaman, Kishore, Vijayaraghavan, Sundeep, Matthew, Jimmy, Dudipala, Raghuveer Reddy, Ramu, Janarthanan, Paul, Jerry, Rajan, Sunil, Verma, Vishak, Chaudary, Ashish, Dhake, Swapnil, Omkumar, Akshay, Kapahtia, Radhika, Sharma, Dimpy, Maharaja, Nirav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Private Ltd. 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938444/
https://www.ncbi.nlm.nih.gov/pubmed/31908365
http://dx.doi.org/10.1055/s-0039-3401474
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author Sharma, Mohit
Iyer, Subramania
Purushottaman, Kishore
Vijayaraghavan, Sundeep
Matthew, Jimmy
Dudipala, Raghuveer Reddy
Ramu, Janarthanan
Paul, Jerry
Rajan, Sunil
Verma, Vishak
Chaudary, Ashish
Dhake, Swapnil
Omkumar, Akshay
Kapahtia, Radhika
Sharma, Dimpy
Maharaja, Nirav
author_facet Sharma, Mohit
Iyer, Subramania
Purushottaman, Kishore
Vijayaraghavan, Sundeep
Matthew, Jimmy
Dudipala, Raghuveer Reddy
Ramu, Janarthanan
Paul, Jerry
Rajan, Sunil
Verma, Vishak
Chaudary, Ashish
Dhake, Swapnil
Omkumar, Akshay
Kapahtia, Radhika
Sharma, Dimpy
Maharaja, Nirav
author_sort Sharma, Mohit
collection PubMed
description Introduction Vascularized composite allotransplantation (VCA) has added another step to the reconstructive ladder, leading to a paradigm shift in the approach toward management of cases of upper limb amputations. In this article, we discuss in detail the technical aspects of proximal forearm level transplantation, as well as the immediate posttransplant monitoring and immunosuppression protocols. Materials and Methods A 24-year-old male victim of an electric injury presented with a bilateral proximal forearm level amputation. After the mandatory preoperative psychiatric and immunological evaluation, the patient underwent a proximal forearm level double upper extremity transplantation. He was then put on a stringent immunosuppression and physical rehabilitative regime. Discussion Conceptually, the proximal forearm level transplantation is significantly different from distal forearm level transplant. This transplant “reestablishes” the “donor extremity length,” maintains the normal functional length of the donor muscles, and the functional return happens only after the newly transplanted donor muscles are reinnervated over a period of time. Conclusion As the sequence of surgical repair and associated decision making could be quite confusing for this level of transplantation, it is highly advisable to do mock cadaver surgical dissections in order to standardize the procedure and make the team familiar with it.
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spelling pubmed-69384442020-01-06 Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation Sharma, Mohit Iyer, Subramania Purushottaman, Kishore Vijayaraghavan, Sundeep Matthew, Jimmy Dudipala, Raghuveer Reddy Ramu, Janarthanan Paul, Jerry Rajan, Sunil Verma, Vishak Chaudary, Ashish Dhake, Swapnil Omkumar, Akshay Kapahtia, Radhika Sharma, Dimpy Maharaja, Nirav Indian J Plast Surg Introduction Vascularized composite allotransplantation (VCA) has added another step to the reconstructive ladder, leading to a paradigm shift in the approach toward management of cases of upper limb amputations. In this article, we discuss in detail the technical aspects of proximal forearm level transplantation, as well as the immediate posttransplant monitoring and immunosuppression protocols. Materials and Methods A 24-year-old male victim of an electric injury presented with a bilateral proximal forearm level amputation. After the mandatory preoperative psychiatric and immunological evaluation, the patient underwent a proximal forearm level double upper extremity transplantation. He was then put on a stringent immunosuppression and physical rehabilitative regime. Discussion Conceptually, the proximal forearm level transplantation is significantly different from distal forearm level transplant. This transplant “reestablishes” the “donor extremity length,” maintains the normal functional length of the donor muscles, and the functional return happens only after the newly transplanted donor muscles are reinnervated over a period of time. Conclusion As the sequence of surgical repair and associated decision making could be quite confusing for this level of transplantation, it is highly advisable to do mock cadaver surgical dissections in order to standardize the procedure and make the team familiar with it. Thieme Medical and Scientific Publishers Private Ltd. 2019-09 2019-12-26 /pmc/articles/PMC6938444/ /pubmed/31908365 http://dx.doi.org/10.1055/s-0039-3401474 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Sharma, Mohit
Iyer, Subramania
Purushottaman, Kishore
Vijayaraghavan, Sundeep
Matthew, Jimmy
Dudipala, Raghuveer Reddy
Ramu, Janarthanan
Paul, Jerry
Rajan, Sunil
Verma, Vishak
Chaudary, Ashish
Dhake, Swapnil
Omkumar, Akshay
Kapahtia, Radhika
Sharma, Dimpy
Maharaja, Nirav
Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation
title Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation
title_full Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation
title_fullStr Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation
title_full_unstemmed Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation
title_short Indian Subcontinent’s First Proximal Forearm Level Double Upper Extremity Transplantation
title_sort indian subcontinent’s first proximal forearm level double upper extremity transplantation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938444/
https://www.ncbi.nlm.nih.gov/pubmed/31908365
http://dx.doi.org/10.1055/s-0039-3401474
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