Nafamostat and sepimostat identified as novel neuroprotective agents via NR2B N-methyl-D-aspartate receptor antagonism using a rat retinal excitotoxicity model

In addition to its role in the treatment of pancreatitis, the serine protease inhibitor nafamostat exhibits a retinal protective effect. However, the exact mechanisms underlying this effect are unknown. In this study, the neuroprotective effects of nafamostat and its orally active derivative sepimos...

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Detalles Bibliográficos
Autores principales: Fuwa, Masahiro, Kageyama, Masaaki, Ohashi, Koji, Sasaoka, Masaaki, Sato, Ryuichi, Tanaka, Masami, Tashiro, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938488/
https://www.ncbi.nlm.nih.gov/pubmed/31892740
http://dx.doi.org/10.1038/s41598-019-56905-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938488/
https://www.ncbi.nlm.nih.gov/pubmed/31892740
http://dx.doi.org/10.1038/s41598-019-56905-x

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