Cargando…

Obesity-induced nucleosome release predicts poor cardio-metabolic health

OBJECTIVE: While circulating nucleosome levels are high in obese mouse models, it is unknown where these nucleosomes originate from and whether they are a marker of cardio-metabolic health in humans. Here, we aimed to determine whether an association exists between circulating nucleosomes and the ri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo Re, Oriana, Maugeri, Andrea, Hruskova, Jana, Jakubik, Juraj, Kucera, Jan, Bienertova-Vasku, Julie, Oben, Jude A., Kubala, Lukas, Dvorakova, Adela, Ciz, Milan, Vinciguerra, Manlio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938639/ https://www.ncbi.nlm.nih.gov/pubmed/31892362 http://dx.doi.org/10.1186/s13148-019-0797-8

Ejemplares similares

Independent Effects of Hypertension and Obesity on Left Ventricular Mass and Geometry: Evidence from the Cardiovision 2030 Study
por: Maugeri, Andrea, et al.
Publicado: (2019)

The Role of Dietary Phenolic Compounds in Epigenetic Modulation Involved in Inflammatory Processes
por: Číž, Milan, et al.
Publicado: (2020)

How dietary patterns affect left ventricular structure, function and remodelling: evidence from the Kardiovize Brno 2030 study
por: Maugeri, Andrea, et al.
Publicado: (2019)

Protein-Rich or Amino-Acid Only Diets Entrain the Liver Clock: Time to Scrap Insulin?
por: Maugeri, Andrea, et al.
Publicado: (2018)

Adipokines as Biomarkers in Health and Disease
por: Bienertova-Vasku, Julie, et al.
Publicado: (2018)

Circulating histone signature of human lean metabolic-associated fatty liver disease (MAFLD)
por: Buzova, Diana, et al.
Publicado: (2020)

A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer Cells
por: Rivas Serna, Irma Magaly, et al.
Publicado: (2020)

Histone MacroH2A1: A Chromatin Point of Intersection between Fasting, Senescence and Cellular Regeneration
por: Lo Re, Oriana, et al.
Publicado: (2017)

Association of Cardiovascular Health with Epicardial Adipose Tissue and Intima Media Thickness: The Kardiovize Study
por: Hruskova, Jana, et al.
Publicado: (2018)

Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults
por: Lo Re, Oriana, et al.
Publicado: (2018)

Macro Histone Variants: Emerging Rheostats of Gastrointestinal Cancers
por: Giallongo, Sebastiano, et al.
Publicado: (2019)

Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin
por: Raffaele, Marco, et al.
Publicado: (2021)

Cardio- and Neurometabolic Adipobiology: Consequences and Implications for Therapy
por: Frohlich, Jan, et al.
Publicado: (2021)

Matrix Metalloproteinase-2 Promoter Genotype as a Marker of Cutaneous T-Cell Lymphoma Early Stage
por: Vasku, Anna, et al.
Publicado: (2010)

Gut Dysbiosis and Adaptive Immune Response in Diet-induced Obesity vs. Systemic Inflammation
por: Pindjakova, Jana, et al.
Publicado: (2017)

The Effects of Meal Timing and Frequency, Caloric Restriction, and Fasting on Cardiovascular Health: an Overview
por: Maugeri, Andrea, et al.
Publicado: (2020)

MiR-21 binding site SNP within ITGAM associated with psoriasis susceptibility in women
por: Hruska, Pavel, et al.
Publicado: (2019)

Osteocalcin levels decrease during the treatment of an acute depressive episode
por: Bartečků, Elis, et al.
Publicado: (2022)

Socioeconomic characteristics, family structure and trajectories of children’s psychosocial problems in a period of social transition
por: Kuruczova, Daniela, et al.
Publicado: (2020)

Assessing Stress in Pregnancy and Postpartum: Comparing Measures
por: Štěpáníková, Irena, et al.
Publicado: (2020)

Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease
por: Bienertová-Vašků, Julie, et al.
Publicado: (2016)

Evolution favours aging in populations with assortative mating and in sexually dimorphic populations
por: Lenart, Peter, et al.
Publicado: (2018)

Predation has small, short-term, and in certain conditions random effects on the evolution of aging
por: Lenart, Peter, et al.
Publicado: (2021)

Learning mitigates genetic drift
por: Lenart, Peter, et al.
Publicado: (2022)

Phosphorylation within Intrinsic Disordered Region Discriminates Histone Variant macroH2A1 Splicing Isoforms—macroH2A1.1 and macroH2A1.2
por: Giallongo, Sebastiano, et al.
Publicado: (2021)

GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways
por: Frohlich, Jan, et al.
Publicado: (2022)

Modulation of metabolic activity of phagocytes by antihistamines
por: Lojek, Antonin, et al.
Publicado: (2011)

Deficiency of histone variant macroH2A1.1 is associated with sexually dimorphic obesity in mice
por: Chiodi, Valentina, et al.
Publicado: (2023)

Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer
por: Slaby, Ondrej, et al.
Publicado: (2012)

MicroRNAs Involved in the Lipid Metabolism and Their Possible Implications for Atherosclerosis Development and Treatment
por: Novák, Jan, et al.
Publicado: (2014)

Homeostatic model of human thermoregulation with bi-stability
por: Hajnová, Veronika, et al.
Publicado: (2021)

Birth weight rather than birth length is associated with childhood behavioural problems in a Czech ELSPAC cohort
por: Ráčková, Lucie, et al.
Publicado: (2021)

Circulating Levels of Agouti-Related Peptide in Endometrial Cancer Survivors
por: Bienertova-Vasku, Julie, et al.
Publicado: (2011)

Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4(+)CD25(+)FoxP3(+) regulatory T cells activation
por: Lo Re, Oriana, et al.
Publicado: (2020)

Detection of cell-free histones in the cerebrospinal fluid of pediatric central nervous system malignancies by imaging flow cytometry
por: Buzova, Diana, et al.
Publicado: (2023)

Mutual Antagonism between Circadian Protein Period 2 and Hepatitis C Virus Replication in Hepatocytes
por: Benegiamo, Giorgia, et al.
Publicado: (2013)

Male mortality rates mirror mortality rates of older females
por: Lenart, Peter, et al.
Publicado: (2019)

Neural Differentiation Is Inhibited through HIF1α/β-Catenin Signaling in Embryoid Bodies
por: Večeřa, Josef, et al.
Publicado: (2017)

Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System
por: Cordero, Paul, et al.
Publicado: (2017)

Proteomic Signatures of Human Visceral and Subcutaneous Adipocytes
por: Hruska, Pavel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a8okl75js1jmdkuqjsfagi7aca