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Linking cancer transcriptional addictions by CDK7 to YAP/TAZ
Inhibition of CDK7 is a promising strategy for cancer therapy. CDK7 so far has been understood mainly in the context of Pol II-driven transcription. However, how are the roles of CDK7 in the “basal” transcriptional machinery reconciled with the function of CDK7 as inducer of specific transcriptional...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938668/ https://www.ncbi.nlm.nih.gov/pubmed/31896688 http://dx.doi.org/10.1101/gad.335562.119 |