CHK2-FOXK axis promotes transcriptional control of autophagy programs

Autophagy is an evolutionarily conserved catabolic process, which plays a vital role in removing misfolded proteins and clearing damaged organelles to maintain internal environment homeostasis. Here, we uncovered the checkpoint kinase 2 (CHK2)–FOXK (FOXK1 and FOXK2) axis playing an important role in...

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Detalles Bibliográficos
Autores principales: Chen, Yuping, Wu, Jinhuan, Liang, Guang, Geng, Guohe, Zhao, Fei, Yin, Ping, Nowsheen, Somaira, Wu, Chengming, Li, Yunhui, Li, Lei, Kim, Wootae, Zhou, Qin, Huang, Jinzhou, Liu, Jiaqi, Zhang, Chao, Guo, Guijie, Deng, Min, Tu, Xinyi, Gao, Xiumei, Liu, Zhongmin, Chen, Yihan, Lou, Zhenkun, Luo, Kuntian, Yuan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938702/
https://www.ncbi.nlm.nih.gov/pubmed/31911943
http://dx.doi.org/10.1126/sciadv.aax5819

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