Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

The tetrapod neuronal protein ARC and its Drosophila melanogaster homolog, dARC1, have important but differing roles in neuronal development. Both are thought to originate through exaptation of ancient Ty3/Gypsy retrotransposon Gag, with their novel function relying on an original capacity for self-...

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Detalles Bibliográficos
Autores principales: Cottee, Matthew A., Letham, Suzanne C., Young, George R., Stoye, Jonathan P., Taylor, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938703/
https://www.ncbi.nlm.nih.gov/pubmed/31911950
http://dx.doi.org/10.1126/sciadv.aay6354

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