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Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamics
BACKGROUND: Increasing research suggests that mitochondrial defect plays a major role in pulmonary hypertension (PH) pathogenesis. Mitochondrial dynamics and quality control have a central role in the maintenance of the cell proliferation and apoptosis balance. However, the molecular mechanism under...
Autores principales: | Chen, Xi, Yao, Jia-Mei, Fang, Xia, Zhang, Cui, Yang, Yu-Shu, Hu, Cheng-Ping, Chen, Qiong, Zhong, Guang-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938735/ https://www.ncbi.nlm.nih.gov/pubmed/31911790 http://dx.doi.org/10.11909/j.issn.1671-5411.2019.12.003 |
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