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Mechanism research of miR‐34a regulates Axl in non‐small‐cell lung cancer with gefitinib‐acquired resistance

BACKGROUND: To investigate the regulatory mechanism behind miR‐34a‐altered Axl levels in non‐small‐cell lung cancer (NSCLC) with gefitinib‐acquired resistance. METHODS: The expression of miR‐34a, Axl, Gas6 and related downstream signaling proteins in the EGFR mutant NSCLC cell lines were determined...

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Detalles Bibliográficos
Autores principales: Xiong, Ran, Sun, Xiang‐xiang, Wu, Han‐ran, Xu, Guang‐wen, Wang, Gao‐xiang, Sun, Xiao‐hui, Xu, Mei‐qing, Xie, Ming‐ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938762/
https://www.ncbi.nlm.nih.gov/pubmed/31777195
http://dx.doi.org/10.1111/1759-7714.13258