Cargando…

Therapeutic Potential of LNP-Mediated Delivery of miR-634 for Cancer Therapy

MicroRNAs (miRNAs) are endogenous small noncoding RNAs that negatively regulate gene expression by interfering with the translation or stability of target transcripts. Some tumor-suppressive miRNAs can concurrently target multiple cancer-promoting genes and may be useful as therapeutic anticancer ag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gokita, Kentaro, Inoue, Jun, Ishihara, Hiroshi, Kojima, Kazuyuki, Inazawa, Johji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938807/ https://www.ncbi.nlm.nih.gov/pubmed/31877409 http://dx.doi.org/10.1016/j.omtn.2019.10.045

Ejemplares similares

Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma
por: Tran, Phuong Xuan, et al.
Publicado: (2022)

Augmentation of lenvatinib efficacy by topical treatment of miR-634 ointment in anaplastic thyroid cancer
por: Kishikawa, Masahiro, et al.
Publicado: (2021)

Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment
por: Inoue, Jun, et al.
Publicado: (2020)

miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer
por: Hiramoto, Hidekazu, et al.
Publicado: (2017)

Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells
por: Liu, Chang, et al.
Publicado: (2021)

circIFT80 Functions as a ceRNA for miR-142, miR-568, and miR-634 and Promotes the Progression of Colorectal Cancer by Targeting β-Catenin
por: Liu, Ning, et al.
Publicado: (2022)

Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma
por: Sakha, Sujata, et al.
Publicado: (2016)

miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway
por: van Jaarsveld, Marijn T. M., et al.
Publicado: (2015)

Expression of miR‐634 in gastric carcinoma and its effects on proliferation, migration, and invasion of gastric cancer cells
por: Guo, Jiao, et al.
Publicado: (2018)

miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein
por: Tonouchi, Erina, et al.
Publicado: (2018)

Publisher Correction: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein
por: Tonouchi, Erina, et al.
Publicado: (2018)

MiR‐634 sensitizes glioma cells to temozolomide by targeting CYR61 through Raf‐ERK signaling pathway
por: Tan, Zhigang, et al.
Publicado: (2018)

Hsa_circ_0084927 Regulates Cervical Cancer Advancement via Regulation of the miR-634/TPD52 Axis
por: Shi, Peijing, et al.
Publicado: (2020)

LncRNA SNHG8 Serves as an Oncogene in Breast Cancer Through miR-634/ZBTB20 Axis
por: Xu, Xianyun, et al.
Publicado: (2021)

Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery
por: Das, Riddha, et al.
Publicado: (2023)

miR-655 Is an EMT-Suppressive MicroRNA Targeting ZEB1 and TGFBR2
por: Harazono, Yosuke, et al.
Publicado: (2013)

The effects of PEGylation on LNP based mRNA delivery to the eye
por: Ryals, Renee C., et al.
Publicado: (2020)

The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma
por: Furuta, Mayuko, et al.
Publicado: (2013)

LncRNA DANCR functions as a competing endogenous RNA to regulate RAB1A expression by sponging miR-634 in glioma
por: Xu, Dawei, et al.
Publicado: (2018)

Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects
por: Kiaie, Seyed Hossein, et al.
Publicado: (2022)

Astrocyte-targeted siRNA delivery by adenosine-functionalized LNP in mouse TBI model
por: Xiao, Hai, et al.
Publicado: (2023)

Regulation of microglia polarization via mannose receptor-mediated delivery of siRNA by ligand-functionalized DoGo LNP
por: Xiao, Hai, et al.
Publicado: (2021)

PT634. Alleviation of neuropathic pain treated with opioid by electroconvulsive therapy
por: Iwata, Ken, et al.
Publicado: (2016)

Feasibility of laparoscopic total gastrectomy in overweight patients: Implications of less impact of overweight on laparoscopic versus open approach
por: Nakagawa, Masatoshi, et al.
Publicado: (2018)

Ionizable Lipids with Triazole Moiety from Click Reaction for LNP-Based mRNA Delivery
por: Wang, Yixiang, et al.
Publicado: (2023)

Down-regulation of LAPTM5 in human cancer cells
por: Nuylan, Michelle, et al.
Publicado: (2016)

Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin
por: Huysmans, Hanne, et al.
Publicado: (2019)

Stable Cavitation-Mediated Delivery of miR-126 to Endothelial Cells
por: He, Stephanie, et al.
Publicado: (2022)

Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia
por: Wang, Xudong, et al.
Publicado: (2023)

Silencing of STAT3 via Peptidomimetic LNP-Mediated Systemic Delivery of RNAi Downregulates PD-L1 and Inhibits Melanoma Growth
por: Ehexige, Ehexige, et al.
Publicado: (2020)

Postoperative Complications of Laparoscopic Total Gastrectomy versus Open Total Gastrectomy for Gastric Cancer in a Meta-Analysis of High-Quality Case-Controlled Studies
por: Inokuchi, Mikito, et al.
Publicado: (2016)

SAT-634 The Effect of Continine Verified Smoking on the Development of Diabetes
por: Jung, Inha, et al.
Publicado: (2020)

Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection
por: Okuda, Masafumi, et al.
Publicado: (2017)

Involvement of Dual Strands of miR-143 (miR-143-5p and miR-143-3p) and Their Target Oncogenes in the Molecular Pathogenesis of Lung Adenocarcinoma
por: Sanada, Hiroki, et al.
Publicado: (2019)

miR-21, Mediator, and Potential Therapeutic Target in the Cardiorenal Syndrome
por: Huang, Cheng-Kai, et al.
Publicado: (2020)

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia
por: Yang, Jialei, et al.
Publicado: (2017)

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure
por: Raso, Andrea, et al.
Publicado: (2019)

Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines
por: Moghimi, S. Moein
Publicado: (2021)

Engineered Dutasteride-Lipid Based Nanoparticle (DST-LNP) System Using Oleic and Stearic Acid for Topical Delivery
por: Noor, Norhayati Mohamed, et al.
Publicado: (2022)

MiR-192, miR-200c and miR-17 are fibroblast-mediated inhibitors of colorectal cancer invasion
por: Ast, Volker, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_acf8e1p6go6smp4tk8kjg8lnpp