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In search for potential antidiabetic compounds from natural sources: docking, synthesis and biological screening of small molecules from Lycium spp. (Goji)
Current clinical antidiabetic drugs, like rosiglitazone 1, have been implicated in some serious side effects like edema, weight gain, and heart failure, making it necessary to find alternative agents. Partial agonists of peroxisome-proliferator activated receptor-gamma (PPARγ) were determined to pos...
Autores principales: | Yalamanchili, Chinni, Chittiboyina, Amar G., Haider, Saqlain, Vasquez, Yelkaira, Khan, Shabana, do Carmo, Jussara M., da Silva, Alexandre A., Pinkerton, Mark, Hall, John E., Walker, Larry A., Khan, Ikhlas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938889/ https://www.ncbi.nlm.nih.gov/pubmed/31909232 http://dx.doi.org/10.1016/j.heliyon.2019.e02782 |
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