C3 Transferase-Expressing scAAV2 Transduces Ocular Anterior Segment Tissues and Lowers Intraocular Pressure in Mouse and Monkey

Glaucoma is a lifelong disease with elevated intraocular pressure (IOP) as the main risk factor, and reduction of IOP remains the major treatment for this disease. However, current IOP-lowering therapies are far from being satisfactory. We have demonstrated that the lentivirus-mediated exoenzyme C3...

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Detalles Bibliográficos
Autores principales: Tan, Junkai, Wang, Xizhen, Cai, Suping, He, Fen, Zhang, Daren, Li, Dongkan, Zhu, Xianjun, Zhou, Liang, Fan, Ning, Liu, Xuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938898/
https://www.ncbi.nlm.nih.gov/pubmed/31909087
http://dx.doi.org/10.1016/j.omtm.2019.11.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938898/
https://www.ncbi.nlm.nih.gov/pubmed/31909087
http://dx.doi.org/10.1016/j.omtm.2019.11.017

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